At a glance
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Evaluation of Serum and Peritoneal Fluid Mannose-binding Lectin Associated Serine Protease-3, Adipsin, Properdin, and Complement Factor H Levels in Endometriosis Patients
In Brief
An observational study evaluating Mannose-binding lectin-associated serine protease-3 (MASP-3) Level, Adipsin Level, and 3 other interventions for Endometriosis and 2 related conditions. Completed, enrolled 58 participants across 1 site.
Detailed Summary
Endometriosis is a chronic gynecological condition affecting nearly 10% of women of reproductive age. A definitive diagnosis of endometriosis requires laparoscopy. Studies aim to identify novel biomarkers to aid in the development of effective noninvasive diagnostic methods. Despite several theories, the full understanding of the etiopathogenesis remains elusive. A distorted immune response is thought to play a crucial role in the pathophysiology of endometriosis. This study aimed to evaluate whether the levels of alternative complement molecules change in the blood serum and peritoneal fluid of endometriosis patients compared to healthy subjects.
Study Details
Timeline
Interventions
Measurement of venous blood serum and peritoneal fluid levels of MASP-3 level by ELISA method.
Measurement of venous blood serum and peritoneal fluid levels of adipsin level by ELISA method.
Measurement of venous blood serum and peritoneal fluid levels of properdin level by ELISA method.
Measurement of venous blood serum and peritoneal fluid levels of CFH level by ELISA method.
Measurement of venous blood serum level of CA-125 level by ELISA method.