CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 256 enrolled
Drug / intervention
Memantine Hydrochloride 10 MG +1 moredrug
Likely dose
Memantine Hydrochloride 10 MGfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06501638
NCT06501638Phase 2Completed
CompareCT.gov

Efficacy and Safety of memanTine in the Treatment Of Frequently symPtomatic Atrial Premature Beats: a Multicenter Randomized Double-blind Placebo-controlled Study

Shanghai East Hospital·interventional·Posted Jul 15, 2024·Updated Nov 25, 2025

In Brief

A Phase 2 clinical trial evaluating Memantine Hydrochloride 10 MG and Placebo for Atrial Premature Beats, Contractions, or Systoles. Completed, enrolled 256 participants across 1 site.

Detailed Summary

A multicenter, randomized, double-blind, placebo-controlled study to expIore the efficacy and safety of Memantine hydrochIoride tabIets to treat patients with frequent PACs.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAtrial Premature Beats, Contractions, or Systoles
CountriesChina
Collaborators--

Timeline

Phase 2CompletedFinished
20252026
First PostedJul 15, 2024
Enrollment StartAug 29, 2024
Primary CompletionMar 21, 2025
Study CompletionMay 16, 2025
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 2.0 years ago

Interventions

Memantine Hydrochloride 10 MGdrug

Take Memantine Hydrochloride for intervention First week, 5mg(half the tablet), p.o.，bid. Second to Sixth week, 10mg(one tablet), p.o., bid

Placebodrug

Take placebo for intervention First week, half the tablet, p.o., bid. Second to Sixth week, one tablet, p.o., bid