At a glance
ClinicalIndex Comparison RecordN/ACompleted· 30 enrolled
Drug / intervention
Colonoscopyprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Investigating the Relationship Between Inflammation and Proteolytic Activity From Mucosa-associated Microbiota in Crohn's Disease Patients
In Brief
An observational study evaluating Colonoscopy for Crohn's Disease of Both Small and Large Intestine. Completed, enrolled 30 participants across 1 site.
Detailed Summary
This study postulates that altered microbiota associated with areas of mucosal inflammation in CD, can be characterized by an increased proteolytic profile. This is clinically important as it may be possible to modulate the proteolytic activity of the CD-associated bacteria by using other bacteria that produce protease inhibitors, such as serpins.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesCanada
Collaborators--
Timeline
N/ACompletedFinished
2020202120222023202420252026
Enrollment StartDec 2019
First PostedJul 2024
Primary CompletionFeb 2025
TodayJul 2026
First PostedJul 16, 2024
Enrollment StartDec 1, 2019
Primary CompletionFeb 20, 2025
TodayJul 2, 2026
Enrollment to primary: 5.2 yearsPosted 2.0 years ago
Interventions
Colonoscopyprocedure
Colonoscopy with video recording and biopsy collection