At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 24 enrolled
Drug / intervention
HFA-152a +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Double-blind, Single-site, Two-way Crossover Phase 1 Study to Assess the Effect of Repeated Doses of Test Propellant (HFA-152a) on Mucociliary Clearance as Compared to Reference Propellant (HFA-134a) in Healthy Male and Female Participants
In Brief
A Phase 1 clinical trial evaluating HFA-152a, HFA-134a, and 1 other intervention for Asthma. Completed, enrolled 24 participants across 1 site.
Detailed Summary
The main goal of the study is to assess the effect of the administration of reference propellant \[HFA-134a (1,1,1,2 - Tetrafluoroethane)\] and test propellant \[HFA-152a (1 - Difluoroethane)\] in healthy adults on mucociliary clearance (MCC).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma
CountriesUnited Kingdom
Collaborators--
Timeline
Phase 1CompletedFinished
20252026
First PostedJul 2024
Enrollment StartJul 2024
Primary CompletionOct 2024
TodayJul 2026
First PostedJul 17, 2024
Enrollment StartJul 29, 2024
Primary CompletionOct 24, 2024
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 2.0 years ago
Interventions
HFA-152aother
HFA-152a is administered via oral inhalation
HFA-134aother
HFA-134a is administered via oral inhalation
Radiolabeled saline solutionother
Radiolabeled saline solution is administered via oral inhalation