CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 21 enrolled / 21 target
Drug / intervention
Isometric handgrip exercise +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06529068
NCT06529068N/ACompletedOn Track (1.1/mo)Completion was 13mo ago

Blood Pressure Responses to Isometric Blood Flow Restriction Exercise

Hirofumi Tanaka·interventional·Posted Jul 31, 2024·Updated Jun 10, 2026

In Brief

A clinical study evaluating Isometric handgrip exercise, Isometric handgrip exercise with a narrow-elastic band, and 1 other intervention for Blood Pressure. Completed, enrolled 21 participants across 1 site.

Detailed Summary

The goal of this interventional study is to evaluate the acute impact of isometric blood flow restriction (BFR) exercise on blood pressure and other cardiovascular functions in healthy young adult volunteers. The main question it aims to answer is: The investigators hypothesize that isometric BFR exercise with a wide-rigid cuff would lead to greater blood pressure and other cardiovascular responses and that these cardiovascular responses would be greater under isometric BFR exercise with narrow-elastic bands compared with the control condition (no cuff). Participants will perform isometric exercises in 3 laboratory visits with different exercise conditions) no cuff control 2) BFR with wide-rigid cuff 3) BFR with narrow-elastic band.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBlood Pressure
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedJul 31, 2024
Enrollment StartDec 2, 2024
Primary CompletionMay 30, 2025
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 1.9 years ago

Arms & Interventions

Isometric exercise without BFR cuff (control)active_comparator

Behavioral: Isometric handgrip exercise
Isometric exercise with narrow-elastic BFR bandexperimental

Behavioral: Isometric handgrip exercise with a narrow-elastic band
Isometric exercise with wide-rigid BFR cuffexperimental

Behavioral: Isometric handgrip exercise with a wide-rigid cuff

Interventions

Isometric handgrip exercisebehavioral

The participants will perform isometric handgrip exercises without blood flow restriction.

Isometric handgrip exercise with a narrow-elastic bandbehavioral

The participants will perform isometric handgrip exercises with blood flow restriction using a narrow-elastic band.

Isometric handgrip exercise with a wide-rigid cuffbehavioral

The participants will perform isometric handgrip exercises with blood flow restriction using a wide-rigid cuff.