CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 2,086 enrolled
Drug / intervention
Penile blockprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06545058
NCT06545058N/ACompleted
CompareCT.gov

Safety Profile of Ropivacaine in Dorsal Penile Nerve Block for Male Circumcision: a Large Cohort Study in Children

Universitair Ziekenhuis Brussel·observational·Posted Aug 9, 2024·Updated Dec 18, 2025

In Brief

An observational study evaluating Penile block for Pain and Necrosis. Completed, enrolled 2,086 participants.

Detailed Summary

Dorsal penile nerve block (DPNB) according to Dalens' technique by using local anesthetics (LAs) is a fundamental part of a multimodal analgesic approach following circumcision. Ropivacaine has a favorable cardiovascular and neurological toxicity profile. However, its application in DPNB is limited because of the theoretical concerns about its vasoconstrictive properties and the potential risks of ischemia of the glans. The aim is to evaluate the incidence of necrosis of the glans penis and the safety profile of ropivacaine following its use in the DPNB in a large pediatric population.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Necrosis
Countries--
Collaborators--

Timeline

N/ACompletedFinished
2000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 9, 2024
Enrollment StartJan 1, 2000
Primary CompletionDec 31, 2021
Study CompletionDec 10, 2025
TodayJul 2, 2026
Enrollment to primary: 22 yearsPosted 1.9 years ago

Interventions

Penile blockprocedure

Penile block with local anesthetics