At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Novel Sperm Selection Method Provides Advantages Over Conventional Approaches: Validation Through a Clinical Pilot Study
In Brief
A clinical study evaluating Density Gradient Centrifugation and CA0 chamber for Male Infertility. Completed, enrolled 115 participants across 1 site.
Detailed Summary
The goal of this clinical trial is to know if a novel sperm selection device (CA0) has a similar performance than the standard selection method in teratozoospermic and azoospermic men. The main questions it aims to answer are: Does the CA0 sperm selection device increases the sperm concentration? Does the CA0 sperm selection device increases the sperm motility? What are the differences in sperm membrane potential when CA0 is used? Do intracellular Calcium levels change when CA0 is used? Does CA0 increase fertilization rates? Researchers will compare CA0 to the standard of care for sperm selection (density gradient centrifugation) to see if CA0 has similar performance Participants will: Provide a semen sample Have their semen sample analyzed, processed and used for assisted reproduction technologies
Study Details
Timeline
Interventions
Sperm separation with density gradients
Sperm separation with a novel device