CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 266 enrolled
Drug / intervention
laparoscopic hybrid surgery (LHS)procedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06550700
NCT06550700N/ACompleted

The Outcomes of Simultaneous Resection for Colorectal Cancer Liver Metastases by Laparoscopic Hybrid Surgery Versus Totally Open Surgery: a Prospective Cohort Study

Changhai Hospital·observational·Posted Aug 13, 2024·Updated Apr 11, 2025

In Brief

An observational study evaluating laparoscopic hybrid surgery (LHS) for Resectable Simultaneous Colorectal Cancer Liver Metastasis. Completed, enrolled 266 participants across 1 site.

Detailed Summary

Simultaneous colorectal cancer liver metastasis (SCRLM) is one of the risk factors for poor prognosis in colorectal cancer. Surgical resection of primary and metastatic lesions is the first choice of treatment for patients with resectable SCRLM. Simultaneous resection of colorectal cancer liver metastases by totally open surgery (TOS) has been widely used. However, we propose that laparoscopic hybrid surgery (LHS) may have better short and long-term outcomes. This study aimed to compare the safety, short-term, and long-term efficacy of LHS versus TOS for patients with resectable SCRLMs.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedAug 13, 2024
Enrollment StartJan 1, 2010
Primary CompletionMay 1, 2024
Study CompletionAug 1, 2024
TodayJul 2, 2026
Enrollment to primary: 14.3 yearsPosted 1.9 years ago

Interventions

laparoscopic hybrid surgery (LHS)procedure

First performed the laparoscopic exploration of the entire abdominal-pelvic cavity to determine the resectability of the primary and metastatic lesions. After the blood vessel detachment and bowel detachment, the distal bowel of the tumor was severed and the pneumoperitoneum was closed. The liver metastases were then removed in both cohorts by open resection through the right subcostal incision.