CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 2 enrolled
Drug / intervention
topical 1% methotrexate gel +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06555497
NCT06555497Early Ph 1Completed

A Pilot Study of Topical 1% Methotrexate Gel Versus Clobetasol Propionate in Patients With Mild-moderate Plaque-type Psoriasis

Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium·interventional·Posted Aug 15, 2024·Updated Aug 16, 2024

In Brief

A Early Phase 1 clinical trial evaluating topical 1% methotrexate gel and clobetasol propionate 0.05% ointment for Pilot Study and Psoriasis. Completed, enrolled 2 participants across 1 site.

Detailed Summary

A pilot study on the formulation of topical methotrexate was conducted. Patients after baseline evaluation were randomly placed into either topical 1% methotrexate gel or clobetasol propionate 0.05% ointment which was applied for 6 weeks. PASI score was assessed at two-week intervals for a total of eight weeks. Blood chemistry parameters, whole abdomen ultrasound, and adverse drug reactions while on treatment and after eight weeks were monitored as secondary outcome measures.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPhilippines
Collaborators--

Timeline

Early Ph 1CompletedFinished
20222023202420252026
First PostedAug 15, 2024
Enrollment StartJan 1, 2022
Primary CompletionDec 31, 2023
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 1.9 years ago

Interventions

topical 1% methotrexate geldrug

topical 1% methotrexate gel

clobetasol propionate 0.05% ointmentdrug

clobetasol propionate 0.05% ointment