CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 36 enrolled
Drug / intervention
Early implant loading +3 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06574815
NCT06574815N/ACompleted

Evaluation of the Effects of the Small Intestine Submucosa (SIS) Biological Membrane on Guided Bone Regeneration (GBR) and Early Loading of Dental Implants in the Maxillary Anterior Region

Beijing Stomatological Hospital, Capital Medical University·interventional·Posted Aug 28, 2024·Updated Aug 30, 2024

In Brief

A clinical study evaluating Early implant loading, Delayed implant loading, and 2 other interventions for Dental Implantation and Guided Bone Regeneration. Completed, enrolled 36 participants across 1 site.

Detailed Summary

The aim of this randomized controlled trial (RCT) is to determine whether early implant loading that shortens the healing period to 6 weeks can be safely and effectively applied to implants with good initial stability in the maxillary anterior region, which undergoes simultaneous guided bone regeneration (GBR), via clinical examination, intraoral scanning, imageological diagnosis, and aesthetic scoring, and to determine the clinical effect of the small intestine submucosa (SIS) biological barrier membrane in such cases involving early loading. This study is expected to provide preliminary guidance on the timing of loading for a single maxillary anterior implant with insufficient bone volume and provide a theoretical basis for the selection of a biological barrier membrane for GBR in such patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedAug 28, 2024
Enrollment StartApr 30, 2023
Primary CompletionAug 2, 2024
Study CompletionAug 16, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 1.8 years ago

Interventions

Early implant loadingprocedure

Patients underwent definitive restoration at 6 weeks after implant surgery (early loading).

Delayed implant loadingprocedure

Patients underwent definitive restoration at 6 months after implant surgery (delayed loading).

GBR using an SIS membraneprocedure

An small intestine submucosa (SIS) membrane was used in the guided bone regeneration (GBR) surgery.

GBR using an Bio-Gide membraneprocedure

An Bio-Gide membrane was used in the guided bone regeneration (GBR) surgery.