At a glance
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Efficacy and Safety of Propofol in Combination With Different Esketamine Doses for Anesthesia During Loop Electrosurgical Excision Procedure
In Brief
A Phase 4 clinical trial evaluating intravenous injection of propofol only and intravenous injection of propofol +esketamine for Esketamine and 2 related conditions. Completed, enrolled 90 participants across 1 site.
Detailed Summary
The goal of this prospective, randomized controlled study study is to investigate the efficacy and safety of propofol combined with different doses of esketamine (ESK) for anesthesia during loop electrosurgical excision procedure (LEEP).Ninety female patients undergoing LEEP were randomly allocated to three groups.It aims to answer :1.The effect of esketamine combined with propofol in respiration, circulation, etc,during LEEP. 2.The appropriate dosage of esketamine when combined with propofol in LEEP anesthesia.
Study Details
Timeline
Interventions
Propofol was administered intravenously 2 mg/kg
intravenous injection of 0.5 mg/kg ESK followed by 1.5 mg/kg of propofol or intravenous injection of 0.25 mg/kg ESK followed by 1.5 mg/kg of propofol