CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 310 enrolled
Drug / intervention
AZD5004 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06579092
NCT06579092Phase 2Completed

A Phase IIb Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety and Tolerability of AZD5004 in Participants Living With Obesity or Overweight With Comorbidity

AstraZeneca·interventional·Posted Aug 30, 2024·Updated Dec 18, 2025

In Brief

A Phase 2 clinical trial evaluating AZD5004 and Placebo for Obesity or Overweight. Completed, enrolled 310 participants across 62 sites in 7 countries.

Detailed Summary

A Phase IIb, global, randomized, parallel-group, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of AZD5004 compared with placebo, given once daily as an oral tablet(s) for 36 weeks, in male and female participants at least 18 years of age who are living with obesity (body mass index \[BMI\] ≥ 30 kg/m2), or overweight (BMI ≥ 27 kg/m2) who have at least 1 weight-related comorbidity

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Canada, Germany, Japan, Taiwan, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20252026
First PostedAug 30, 2024
Enrollment StartOct 8, 2024
Primary CompletionNov 21, 2025
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 1.8 years ago

Interventions

AZD5004drug

AZD5004 film-coated tablet once daily during 36 weeks

Placebodrug

Placebo matching AZD5004 film-coated tablet once daily during 36 weeks