CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 40 enrolled / 40 target
Drug / intervention
Krill oil +1 moredrug
Likely dose
Krill oil 4 grams orally per dayAI-extracted
Key inclusion· 5
  • Age ≥60 years
  • Chronic musculoskeletal pain of hip, knees, or lower back lasting >3 months
  • Average pain ≥4 on 0-10 numeric rating scale
  • Moderate mobility limitations with Short Physical Performance Battery score 4-10
Key exclusion· 12
  • Known coagulation or bleeding disorders
  • Currently on anticoagulants or full-dose aspirin
  • Regular opioid or high-dose NSAID use
  • Medications affecting muscle (e.g., steroids)

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06580912
NCT06580912Phase 2CompletedHigh Momentum (2.3/mo)Completion was 6mo ago

Krill Oil for Pain and Physical Function in Older Adults

University of Florida·interventional·Posted Aug 30, 2024·Updated Jun 17, 2026

In Brief

A Phase 2 clinical trial evaluating Krill oil and Mixed vegetable oil for Chronic Musculoskeletal Pain. Completed, enrolled 40 participants across 1 site.

Signals

Enrolling ahead of pace

Detailed Summary

Chronic musculoskeletal pain contributes to mobility disability among older adults. Nutritional interventions, like omega-3 fatty acids, may help manage pain and improve physical function. Supplementation with krill oil may offer advantages to fish oil due to better absorption and additional nutrients. This pilot study aims to assess the feasibility of a clinical trial to determine the impact of krill oil supplementation on pain and function in older adults, informing future research.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20252026
First PostedAug 30, 2024
Enrollment StartJan 17, 2025
Primary CompletionDec 17, 2025
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 1.8 years ago

Arms & Interventions

Krill oilexperimental

4 grams of krill oil per day

Drug: Krill oil
Mixed vegetable oilplacebo_comparator

4 grams of mixed vegetable oil per day

Dietary Supplement: Mixed vegetable oil

Interventions

Krill oildrug

4 grams of krill oil per day

Mixed vegetable oildietary

4 grams of mixed vegetable oil per day