CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 210 enrolled
Drug / intervention
Travoprost Intracameral Implant exchanged at Month 12 +6 moredrug
Likely dose
Travoprost Intracameral Implant exchanged at Month 12 75 mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06582732
NCT06582732Phase 2Completed
CompareCT.gov

Prospective, Non-Randomized, Open-Label, Single Center Study to Evaluate the Performance of the Travoprost Intraocular Implant

Glaukos Corporation·interventional·Posted Sep 3, 2024·Updated Oct 15, 2024

In Brief

A Phase 2 clinical trial evaluating Travoprost Intracameral Implant exchanged at Month 12, Travoprost Intracameral Implant exchanged at Month 3, and 5 other interventions for Glaucoma, Open-Angle and Ocular Hypertension. Completed, enrolled 210 participants across 1 site.

Detailed Summary

To evaluate the performance of the Travoprost Intracameral Implant by determining residual drug in explanted implants of the Travoprost Intracameral Implant and by determining aqueous humor concentrations of travoprost free acid at specified timepoints post administration through 24 months

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGlaucoma, Open-Angle, Ocular Hypertension
CountriesArmenia
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedSep 3, 2024
Enrollment StartMar 10, 2021
Primary CompletionNov 2, 2023
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 1.8 years ago

Interventions

Travoprost Intracameral Implant exchanged at Month 12drug

intracameral implant containing travoprost 75 mcg implanted on Day 1 and exchanged at Month 12

Travoprost Intracameral Implant exchanged at Month 3drug

intracameral implant containing travoprost 75 mcg implanted on Day 1 and exchanged at Month 3

Travoprost Intracameral Implant exchanged at Month 6drug

intracameral implant containing travoprost 75 mcg implanted on Day 1 and exchanged at Month 6

Travoprost Intracameral Implant exchanged at Month 24drug

intracameral implant containing travoprost 75 mcg implanted on Day 1 and exchanged at Month 24

Travoprost intracameral implant exchanged at Month 21drug

intracameral implant containing travoprost 75 mcg implanted on Day 1 and exchanged at Month 21

Travoprost intracameral implant exchanged at Month 18drug

intracameral implant containing travoprost 75 mcg implanted on Day 1 and exchanged at Month 18

Travoprost intracameral implant exchanged at Month 15drug

intracameral implant containing travoprost 75 mcg implanted on Day 1 and exchanged at Month 15