CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 279 enrolled
Drug / intervention
Ixekizumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06588296
NCT06588296Phase 3Completed

Efficacy and Safety of Ixekizumab or Ixekizumab Concomitantly Administered With Tirzepatide in Adult Participants With Active Psoriatic Arthritis and Obesity or Overweight: A Phase 3b, Randomized, Multicenter, Open-Label Study (TOGETHER-PsA)

Eli Lilly and Company·interventional·Posted Sep 19, 2024·Updated May 13, 2026

In Brief

A Phase 3 clinical trial evaluating Ixekizumab and Tirzepatide for Psoriatic Arthritis and Obesity. Completed, enrolled 279 participants across 86 sites in 2 countries.

Detailed Summary

The main purpose of this study is to demonstrate that when participants with psoriatic arthritis and obesity or overweight in the presence of at least 1 weight-related comorbid condition receive ixekizumab and tirzepatide concomitantly administered, participants see improvement in their psoriatic arthritis and achieve weight reduction compared to when receiving ixekizumab. Participation in this study includes up to 12 visits and could last up to 61 weeks including screening, open label treatment period, and post-treatment follow-up period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPuerto Rico, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20252026
First PostedSep 19, 2024
Enrollment StartSep 24, 2024
Primary CompletionNov 18, 2025
Study CompletionApr 23, 2026
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 1.8 years ago

Interventions

Ixekizumabdrug

Administered SC

Tirzepatidedrug

Administered SC