CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 175 enrolled
Drug / intervention
Test toothpaste +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06602466
NCT06602466N/ACompleted
CompareCT.gov

A 4-Week Randomised, Controlled, Examiner-blind, Clinical Study Investigating the Efficacy of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health

HALEON·interventional·Posted Sep 19, 2024·Updated Jan 22, 2026

In Brief

A clinical study evaluating Test toothpaste and Colgate Cavity Protection Toothpaste for Dental Plaque and Gingivitis. Completed, enrolled 175 participants across 1 site.

Detailed Summary

The aim of this 4-week clinical study is to evaluate the ability of an experimental toothpaste, containing 0.454 percent (%) Stannous Fluoride (SnF2), 0.3% Zinc Chloride (ZnCl2) and 1% Alumina, to improve gingival health and plaque accumulation compared to a regular fluoride toothpaste (negative control) in participants with plaque-induced mild to moderate gingivitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDental Plaque, Gingivitis
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedSep 19, 2024
Enrollment StartSep 23, 2024
Primary CompletionDec 13, 2024
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 1.8 years ago

Interventions

Test toothpastedrug

0.454% Stannous Fluoride, 0.3% Zinc Chloride,1% Alumina toothpaste containing 1100 parts per million (ppm) fluoride.

Colgate Cavity Protection Toothpastedrug

Commercial toothpaste containing 1450 ppm fluoride.