At a glance
ClinicalIndex Comparison RecordN/ACompleted· 142 enrolled
Drug / intervention
Esketamine +1 moredrug
Likely dose
Esketamine 0.3mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of a Single Dose of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery: a Randomized Controlled Trial
In Brief
A clinical study evaluating Esketamine and normal saline for Depression, Anxiety and 2 related conditions. Completed, enrolled 142 participants across 2 sites.
Detailed Summary
A multicenter, randomized controlled, blinded prospective study to investigate the effects of esketamine on perioperative anxiety and depression in patients undergoing cardiac valve surgery.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression, Anxiety, Cardiac Surgery, S-ketamine
CountriesChina
CollaboratorsBeijing Tiantan Hospital, Navy General Hospital, Beijing
Timeline
N/ACompletedFinished
20252026
First PostedSep 2024
Enrollment StartSep 2024
Primary CompletionApr 2025
Study CompletionApr 2025
TodayJul 2026
First PostedSep 23, 2024
Enrollment StartSep 23, 2024
Primary CompletionApr 7, 2025
Study CompletionApr 30, 2025
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 1.8 years ago
Interventions
Esketaminedrug
A single dose of 0.3mg / kg esketamine during induction of anesthesia.
normal salinedrug
Receiving the same volume of normal saline during induction of anesthesia.