CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 90 enrolled
Drug / intervention
Test Dentifrice (Sensodyne Repair and Protect Original Mint) +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06608368
NCT06608368Phase 4Completed
CompareCT.gov

A Randomized, Controlled Clinical Study Assessing the Effects of a Marketed Dentifrice Compared to a Regular Fluoride Dentifrice and a Positive Control Dentifrice on Tooth Sensitivity While Undergoing Tooth Bleaching

HALEON·interventional·Posted Sep 23, 2024·Updated Dec 15, 2025

In Brief

A Phase 4 clinical trial evaluating Test Dentifrice (Sensodyne Repair and Protect Original Mint), Positive Control Dentifrice (Sensodyne Fresh Mint), and 1 other intervention for Dentin Sensitivity. Completed, enrolled 90 participants across 1 site.

Detailed Summary

The aim of this study is to investigate the efficacy of a marketed dentifrice containing 5 percent (%) NovaMin (Calcium Sodium Phosphosilicate) to reduce tooth sensitivity during and post tooth bleaching compared to a marketed dentifrice containing 5% potassium nitrate (KNO3) and a marketed regular fluoride-containing dentifrice.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDentin Sensitivity
CountriesCanada
Collaborators--

Timeline

Phase 4CompletedFinished
20252026
First PostedSep 23, 2024
Enrollment StartOct 7, 2024
Primary CompletionNov 15, 2024
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 1.8 years ago

Interventions

Test Dentifrice (Sensodyne Repair and Protect Original Mint)drug

Dentifrice containing 5% w/w NovaMin (Calcium Sodium Phosphosilicate) and 1040 ppm fluoride as sodium fluoride.

Positive Control Dentifrice (Sensodyne Fresh Mint)drug

Dentifrice containing 5% w/w KNO3 and 1150 ppm fluoride as sodium fluoride.

Reference Dentifrice (Crest Cavity Protection Regular)drug

Dentifrice containing 1100 ppm fluoride as sodium fluoride.