CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Biphasic transcutaneous auricular vagus nerve stimulation +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06614933
NCT06614933N/ACompleted

How Does the Type of Waveform Affect Tolerability With Transcutaneous Auricular Vagus Nerve Stimulation?

University of Miami·interventional·Posted Sep 26, 2024·Updated May 28, 2026

In Brief

A clinical study evaluating Biphasic transcutaneous auricular vagus nerve stimulation and Monophasic transcutaneous auricular vagus nerve stimulation for Healthy. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS). The research team is interested in how the different forms affect comfort and tolerability, as well as how well it works.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedSep 26, 2024
Enrollment StartDec 15, 2024
Primary CompletionJun 7, 2025
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 1.8 years ago

Interventions

Biphasic transcutaneous auricular vagus nerve stimulationdevice

Transauricular vagus nerve stimulation (taVNS) is a simple technique in which small surface electrodes are placed over the skin of the ear that are thought to be innervated by the auricular branch of the vagus nerve (ABVN). Participants in this group will first receive taVNS with a biphasic current, continuous at 25 Hz, for 1 hour, in-person.

Monophasic transcutaneous auricular vagus nerve stimulationdevice

Transauricular vagus nerve stimulation (taVNS) is a simple technique in which small surface electrodes are placed over the skin of the ear that are thought to be innervated by the auricular branch of the vagus nerve (ABVN). Participants in this group will first receive taVNS with a monophasic current, with a 50% duty cycle at 25 Hz, for 1-hour, in-person.