At a glance
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Effectiveness Of Intravenous Vs Rectal Acetaminophen For Pain Management In Post Operative Neonates; A Randomised Controlled Trial
In Brief
A clinical study evaluating Acetaminophen Suppositories and Acetaminophen Injection for Pain Score Reduction and 4 related conditions. Completed, enrolled 64 participants across 1 site.
Detailed Summary
This randomized controlled trial aims to evaluate the effectiveness of intravenous (IV) versus rectal acetaminophen for postoperative pain management in neonates. The study includes postoperative term neonates who require analgesia for at least 12 hours. The main questions the study seeks to answer are: Does IV acetaminophen provide better pain relief compared to rectal administration in neonates? What is the time to rescue analgesia and the efficacy of pain score reduction between these two routes? The study compares 32 neonates receiving IV acetaminophen to 32 neonates administered rectal acetaminophen. Both routes are administered at equivalent bioavailable doses to ensure a fair comparison.
Study Details
Timeline
Interventions
Per rectal suppositories
Intra-venous injection