At a glance
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Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
In Brief
A clinical study evaluating Transthoracic Echocardiography, Ringer lactate 1000 ml, and 2 other interventions for Pregnancy and 4 related conditions. Completed, enrolled 162 participants across 1 site.
Detailed Summary
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5). In this study, we aim to evaluate the effect of intravenous administration of albumin as a colloid preload on the maternal stroke volume (SV) and cardiac output (CO) versus crystalloid coload. We used TTE to measure the changes in SV, and CO at baseline and at subsequent time points after spinal anesthesia.
Study Details
Timeline
Interventions
Transthoracic Echocardiography will be used to measure the changes in stroke volume and cardiac output.
Patients will receive 1000 mL of Ringer's lactate solution over 15 minutes.
Patients will receive 250 mL of human albumin 5% over 10 minutes
Patients will receive 750 mL of Ringer's lactate solution over 15 minutes.