CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 17 enrolled
Drug / intervention
Apically positioned flap +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06694623
NCT06694623N/ACompleted

Keratinized Tissue Regeneration Following Apically Positioned Flap with and Without Free Gingival Graft Strip: a Split Mouth Randomized Clinical Trial

Adam Malesevic·interventional·Posted Nov 19, 2024·Updated Nov 19, 2024

In Brief

A clinical study evaluating Apically positioned flap and Apically positioned flap with FGG strip for Keratinized Mucosa. Completed, enrolled 17 participants across 1 site.

Detailed Summary

In non-implant edentulous patients reduction of height and width of residual alveolar ridge and reduced attached KT compromise the denture-bearing area unambiguously leading to decrease in full denture stability and retention. Furthermore, in implant edentulous patients insufficient KT is associated with increased plaque accumulation, tissue inflammation, soft tissue recession, marginal bone loss and increased prevalence of peri-implantitis. The present study aimed to evaluate keratinized tissue gain and the wound contraction rate between apically positioned flap without and with free gingival graft strip over a 6-month follow up period. This research was designed as split mouth controlled clinical study included 17 patients having edentulous upper jaw with reduced width of keratinized tissue ( ≤ 4mm measured from middle of the crest to the buccal mucogingival junction or ≤ 2mm from occluso-buccal edge of the alveolar ridge to the mucogingival junction). In each patient, both surgical techniques, apically positioned flap without and with free gingival graft strip, were applied simultaneously. The change of keratinized tissue width and wound contraction rate were measured 30, 60 , 90 and 180 days after surgery

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSerbia

Timeline

N/ACompletedFinished
202420252026
First PostedNov 19, 2024
Enrollment StartMar 1, 2023
Primary CompletionDec 15, 2023
Study CompletionOct 10, 2024
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 1.6 years ago

Interventions

Apically positioned flapprocedure

The split thickness flap was apically positioned as much as possible and sutured to the periosteum utilizing T-mattress sutures.

Apically positioned flap with FGG stripprocedure

The split thickness flap was apically positioned as much as possible and sutured to the periosteum utilizing T-mattress sutures. FGG strip was sutured to the apical end of recipient bed.