At a glance
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The Role of Nerve Block-Constructed Precision Anesthesia on Perioperative Organ Protection in Hip Surgery
In Brief
A clinical study evaluating Combined Lumbar Plexus and Sacral Plexus Block, iliac fascial block, and 1 other intervention for Elderly (People Aged 65 or More) and 4 related conditions. Completed, enrolled 90 participants across 2 sites.
Detailed Summary
The goal of this clinical trial is to investigate the effect of three anesthetic strategies on organ protection in elderly patients undergoing hip fracture surgery. The main questions it aims to answer are: 1.Does the nerve block anesthesia group have a protective effect on the incidence of postoperative delirium in elderly patients undergoing hip surgery? 2.Does the nerve block anesthesia group also provide protective effects on other organs for elderly patients undergoing hip surgery? 3.What effects will these anesthetic strategies have on short-term and long-term prognosis of elderly patients undergoing hip surgery? The investigators will compare it with the spinal anesthesia group and the general anesthesia group to see which has a better protective effect on organs. Participants will undergo preoperative interviews and will be interviewed twice daily, in the morning and evening, from postoperative day 1 to 7 or until discharge, to assess the occurrence of delirium and cognitive levels, pain intensity, and sleep status. Interventions: 1. Nerve block anesthesia group (NA group): Combined Lumbar and Sacral Plexus Block + sedation or laryngeal mask anesthesia 2. General anesthesia group (GA group): General anesthesia (Endotracheal intubation) + iliac fascial block 3. Spinal anesthesia group (SA group): Spinal anesthesia without any nerve blockade
Study Details
Timeline
Interventions
This intervention of Combined Lumbar Plexus and Sacral Plexus Block is assigned to Nerve block anesthesia group (NA group): A combined Lumbar Plexus Block (0.33% Ropivacaine 30ml) and Sacral Plexus Block (0.33% Ropivacaine 20ml) administered as a single injection.
iliac fascial block administered as a single injection below the iliac fascial with 0.33% ropivacaine 30ml.
Spinal anesthesia was performed as a standard care of spinal anesthetic. The spinal puncture site is at L2-3 or L3-4. After the puncture needle reaches the subarachnoid space, 1% ropivacaine 0.8-2 ml, totaling 8-20mg, is injected. Depending on the center's practice, it may be replaced with an equivalent dose of bupivacaine .