At a glance
ClinicalIndex Comparison RecordN/ACompleted· 107 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Active MMP-8 in Oral Fluid for the Detection of Oral and Oropharyngeal Cancer
In Brief
An observational study for Oropharyngeal Cancers and 3 related conditions. Completed, enrolled 107 participants across 1 site.
Detailed Summary
The goal of this observational study is to evaluate whether the active-matrix metalloproteinase-8 (aMMP-8) mouth-rinse test can help detect oral and oropharyngeal cancers. Researchers measured aMMP-8 levels in mouth-rinse samples collected from 77 cancer participants and 50 non-cancer participants in a clinical setting. The main question this study seeks to answer: Can the aMMP-8 mouth-rinse test accurately identify and differentiate cancer participants from non-cancer participants in real-time?
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsOropharyngeal Cancers, Biomarker in Early Diagnosis, Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Periodontal Diseases
CountriesFinland
CollaboratorsKarolinska Institutet, University of Helsinki
Timeline
N/ACompletedFinished
2023202420252026
Enrollment StartMar 2022
Primary CompletionSep 2024
Study CompletionSep 2024
First PostedNov 2024
TodayJul 2026
First PostedNov 22, 2024
Enrollment StartMar 28, 2022
Primary CompletionSep 1, 2024
Study CompletionSep 18, 2024
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 1.6 years ago