At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Double-blind, Randomized Controlled Pilot Study Comparing the Safety and Efficacy of Intracameral Levofloxacin and Intracameral Cefazolin in Cataract Surgery
In Brief
A Early Phase 1 clinical trial evaluating Safety of intracameral levofloxacin in cataract surgery and Use of intracameral cefazolin in cataract surgery for Cataract. Completed, enrolled 50 participants across 2 sites.
Detailed Summary
Patients with senile cataracts undergoing phacoemulsification were assigned to receive intracameral levofloxacin (0.1ml/0.5mg) or intracameral cefazolin (0.1ml/1mg). The primary endpoint was the occurrence of endophthalmitis during the 3 month follow-up period. Secondary endpoints included best-corrected visual acuity (BVCA), the presence of anterior chamber (AC) inflammation with grading of AC cells and presence of flare, along with intraocular pressure (IOP), corneal cell thickness (CCT), central foveal thickness (CFT) and cell density.
Study Details
Timeline
Interventions
Intracameral levofloxacin (0.1ml/0.5mg)
Intracameral cefazolin (0.1ml/1mg)