CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 244 enrolled
Drug / intervention
Robitussin Maximum Strength Cough and Chest Congestion DM +2 moredrug
Likely dose
Robitussin Maximum Strength Cough and Chest Congestion DM 20 milligramfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06716645
NCT06716645Phase 4Completed

A Real-World Evidence Study Evaluating Quality of Life Parameters Following Treatment With Robitussin

HALEON·interventional·Posted Dec 4, 2024·Updated Feb 20, 2026

In Brief

A Phase 4 clinical trial evaluating Robitussin Maximum Strength Cough and Chest Congestion DM and Robitussin Maximum Strength Nighttime Cough DM for Common Cold and Cough. Completed, enrolled 244 participants across 1 site.

Detailed Summary

The purpose of this Real-World Evidence study is to generate real world data from participants with cough associated with the common cold, evaluating the effects in two arms with commercially available cough syrups on health-related quality of life (QoL). Arm 1 includes one cough syrup (which can be used day or night) and Arm 2 includes the daytime cough syrup and a nighttime cough syrup.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCommon Cold, Cough
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20252026
First PostedDec 4, 2024
Enrollment StartDec 4, 2024
Primary CompletionFeb 14, 2025
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 1.6 years ago

Interventions

Robitussin Maximum Strength Cough and Chest Congestion DMdrug

Dextromethorphan Hydrobromide, United States Pharmacopeia (USP) 20 milligram (mg) and Guaifenesin, USP 400 mg

Robitussin Maximum Strength Cough and Chest Congestion DMdrug

Dextromethorphan Hydrobromide, USP 20 mg and Guaifenesin, USP 400 mg

Robitussin Maximum Strength Nighttime Cough DMdrug

Dextromethorphan Hydrobromide, USP 30 mg and Doxylamine Succinate, USP 12.5 mg