CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 40 target
Drug / intervention
Professional mechanical plaque removal and Laser +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06719674
NCT06719674N/AActiveMonitorCompletion was 1mo ago
Slow Enrollment

Impact of Diode Laser as an Adjunct to Professional Mechanical Plaque Removal (PMPR) in Patients With Periodontitis: A Randomized Clinical Trial

University of Sulaimani·interventional·Posted Dec 6, 2024·Updated May 4, 2026

In Brief

A clinical study evaluating Professional mechanical plaque removal and Laser and Professional mechanical plaque removal for Periodontitis and Pocket, Periodontal. Active but no longer recruiting, targeting 40 participants across 1 site.

Signals

Enrolling slower than its timeline implies

Detailed Summary

This study will utilize diode laser to determine its effects on improving periodontal parameters and inflammatory biomarkers, comparing with conventional treatment alone, and evaluate its effectiveness in improving periodontal disease's clinical parameters. Several studies have compared the effects of lasers and conventional periodontal treatment, comparing only its microbiological and clinical parameter levels and therapy to determine their effectiveness in key periodontal pathogens eradication and their effects on improving the clinical parameters of periodontal disease, in this study, salivary biomarkers will be collected and assessed to do a comparison between two treatment modalities. To the best of our knowledge, this is the first study to examine the effect of diode lasers on salivary biomarker levels.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIraq

Timeline

N/AActive
202520262027
First PostedDec 6, 2024
Enrollment StartJan 1, 2025
Primary CompletionJun 1, 2026
Study CompletionDec 1, 2026
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 1.6 years ago

Interventions

Professional mechanical plaque removal and Laserprocedure

A diode laser will be used as an adjunct to mechanical plaque removal.

Professional mechanical plaque removalprocedure

The patients will be treated in accordance with treatment guidelines for Stage III periodontitis issued by the European Federation of Periodontology (13). At baseline, oral hygiene instructions were given together with supra- and subgingival professional mechanical plaque removal (PMPR) using a combination of the ultrasonic scaler and hand instruments, according to the clinical situation. After completing treatment, patients will be asked to return at 1 month for review and again at 3 months to repeat the measurement of clinical parameters and collection of the saliva samples.