CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 87 enrolled
Drug / intervention
Bromfenac +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06785090
NCT06785090Phase 4Completed

Effects of Topical Bromfenac Solution on Macular Thickness in Cataract Patients Undergoing Phacoemulsification Surgery

Inas Abd·interventional·Posted Jan 20, 2025·Updated May 6, 2025

In Brief

A Phase 4 clinical trial evaluating Bromfenac, Moxifloxacin 0.5% ophthalmic solution, and 1 other intervention for Cataract and Cystoid Macular Edema After Phacoemulsification. Completed, enrolled 87 participants across 1 site.

Detailed Summary

The goal of this clinical trial is to learn if bromfenac ophthalmic solution can prevent cystoid macular edema (CME) and reduce macular thickness in patients undergoing phacoemulsification surgery for cataract removal. The main questions it aims to answer are: Does bromfenac reduce the incidence of CME after cataract surgery? Does bromfenac effectively control macular thickness postoperatively compared to standard care? investigators will compare the effects of bromfenac ophthalmic solution to a control group receiving standard postoperative treatment to see if bromfenac provides additional benefits. Participants will: Use bromfenac ophthalmic solution as prescribed postoperatively. Attend follow-up visits for macular thickness measurements and assessments of eye health. Undergo routine postoperative evaluations to monitor for adverse effects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIraq
Collaborators--

Timeline

Phase 4CompletedFinished
202420252026
First PostedJan 20, 2025
Enrollment StartMay 1, 2023
Primary CompletionJan 31, 2024
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 1.4 years ago

Interventions

Bromfenacdrug

Bromfenac is a non-steroidal anti-inflammatory drug (NSAID) formulated as a 0.09% ophthalmic solution. It is administered to reduce inflammation and prevent cystoid macular edema (CME) following cataract surgery.

Moxifloxacin 0.5% ophthalmic solutiondrug

antibiotic, standard postoperative care regimen

Dexamethasone phosphate 0.1%drug

steroid, standard postoperative care regimen