At a glance
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Application of Gaseous Ozone in the Surgical Extraction of Impacted Mandibular Third Molars: Impact on the Incidence of Postoperative Complications and Healing Processes
In Brief
A Phase 3 clinical trial evaluating Ozone and Placebo for Impacted Mandibular Third Molar Extraction. Completed, enrolled 20 participants across 1 site.
Detailed Summary
The goal of this clinical trial is to learn if use of ozone works to treat complications after impacted mandibular third molar surgery. It will also learn does ozone has positive effect on wound healing and quality of life. The main questions it aims to answer are: * Does ozone reduce incidence of postoperative compliactions such as pain, swelling or reduced mouth opening after impacted mandibular third molar surgery? * Does ozone improve wound healing after impacted mandibular third molar surgery? * Does ozone have positive effect on quality of life after impacted mandibular third molar surgery? Participants will: * Receive ozone after impacted mandibular third molar surgery. * Visit the clinic 1st, 3rd, and 7th days after the intervention for checkups and tests. * Keep a diary of their symptoms.
Study Details
Timeline
Arms & Interventions
After the surgical extraction of the impacted mandibular third molar, gaseous ozone will be applied at the extraction site. Ozone will be reapplied 3 days after the intervention, according to the manufacturer's recommendation for wound treatment following tooth extraction.
After the surgical extraction of the impacted mandibular third molar, a sham ozone therapy will be applied at the extraction site. The sham ozone therapy will also be reapplied 3 days after the surgical intervention.
Interventions
In Ozone group, ozone will be applied at the site of the extraction wound for 30 seconds after the surgical extraction of the third molar, according to the manufacturer's recommendation for wound treatment following tooth extraction.
In the control group, a sham ozone therapy will be applied at the site of the extraction wound for 30 seconds after the surgical extraction of the third molar .