CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 132 enrolled
Drug / intervention
Cryotherapy +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06820996
NCT06820996N/ACompleted

Effect of Cryotreated Sodium Hypochlorite Irrigation at Different Consentrations in Mandibular First Molars With Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial

Cukurova University·interventional·Posted Feb 11, 2025·Updated Feb 14, 2025

In Brief

A clinical study evaluating Cryotherapy and Control (Standard treatment) for Pulpitis - Irreversible. Completed, enrolled 132 participants across 1 site.

Detailed Summary

The goal of this clinical trial was to evaluate the effect of cryotreated sodium hypochlorite solution on the intensity of postoperative pain in root canal treatment procedures in mandibular first molar teeth with symptomatic irreversible pulpitis. The main question it aims to answer is: \- Does controlled irrigation with cold sodium hypochlorite in root canal treatment reduce the severity of postoperative pain? In the cryotreated NaOCl group, unlike the normal NaOCl group, the root canals were irrigated with 2 °C NaOCl solution.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTurkey (Türkiye)
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedFeb 11, 2025
Enrollment StartMar 18, 2024
Primary CompletionNov 18, 2024
Study CompletionJan 15, 2025
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 1.4 years ago

Interventions

Cryotherapyother

The root canals were irrigated with 2 °C NaOCl solution in cryotherapy group.

Control (Standard treatment)other

The root canals were irrigated with 25 °C NaOCl solution in normal group.