CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
SOC and Type-I Collagen-based Skin Substitute +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06831760
NCT06831760N/ACompleted

A Randomized, Controlled Clinical Trial Evaluating the Efficacy of Type-I Collagen-based Skin Substitute vs. Dehydrated Human Amnion/Chorion Membrane in the Treatment of Venous Leg Ulcers

Dr Naveen Narayan MS, MCh (Plastic Surgery)·interventional·Posted Feb 18, 2025·Updated Sep 22, 2025

In Brief

A clinical study evaluating SOC and Type-I Collagen-based Skin Substitute and SOC and Human Amnion/Chorion Membrane for Venous Leg Ulcers. Completed, enrolled 60 participants across 1 site.

Detailed Summary

Venous leg ulcers are chronic wounds caused by venous insufficiency, leading to significant morbidity. The purpose of this randomized, controlled study is to evaluate the safety and efficacy of the application of Type-I Collagen-based Skin Substitute (HPTC) vs. Dehydrated Human Amnion/Chorion Membrane (dHCAM) in the treatment of VLUs and to compare their efficacy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndia
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedFeb 18, 2025
Enrollment StartFeb 1, 2025
Primary CompletionJun 30, 2025
Study CompletionJul 10, 2025
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 1.4 years ago

Interventions

SOC and Type-I Collagen-based Skin Substitutedevice

The SOC in this study is wound care covering with High Purity Type-I Collagen-based Skin Substitute applied weekly or as needed followed by a padded 3-layer dressing comprised of first layer - non-adherent and porous, second layer - absorbent 4x4 gauze pads \& third layer - soft roll and compressive wrap

SOC and Human Amnion/Chorion Membranedevice

The SOC in this study is wound care covering with Dehydrated Human Amnion/Chorion Membrane followed by a padded 3-layer dressing comprised of first layer - non-adherent and porous, second layer - absorbent 4x4 gauze pads \& third layer - soft roll and compressive wrap