At a glance
ClinicalIndex Comparison RecordN/ACompleted· 29 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta·observational·Posted Mar 4, 2025·Updated Feb 11, 2026
In Brief
An observational study for Hydrocephalus and Normal Pressure Hydrocephalus. Completed, enrolled 29 participants across 1 site.
Detailed Summary
The goal of this observational study is to evaluate the role of DTI-ALPS in the diagnostic and therapeutic management of NPH The main questions it aims to answer are: * Whether the glymphatic system (GS) is actually impaired in NPH * Whether DTI-ALPS index can predict the positive response to tap test (TT) and to ventriculo-peritoneal shunt (VPS) surgery. A healthy control group of patients (HC group) matched for age with the study group, will undergo MR with DTI-ALPS study
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsHydrocephalus, Normal Pressure Hydrocephalus
CountriesItaly
Collaborators--
Timeline
N/ACompletedFinished
20222023202420252026
Enrollment StartJun 2021
Primary CompletionAug 2024
Study CompletionDec 2024
First PostedMar 2025
TodayJul 2026
First PostedMar 4, 2025
Enrollment StartJun 15, 2021
Primary CompletionAug 31, 2024
Study CompletionDec 31, 2024
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 1.3 years ago