CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
compression productsother
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06873984
NCT06873984N/ACompleted

Compression Stockings for Preventing Lower Limb Lymphedema in Women Treated for Gynecological Malignancies

Joanna Kurpiewska-Pieniążek·interventional·Posted Mar 13, 2025·Updated Mar 13, 2025

In Brief

A clinical study evaluating compression products for Lymphedema. Completed, enrolled 60 participants across 2 sites.

Detailed Summary

The goal of this clinical trial was to evaluate whether compression stockings (23-32 mmHg) reduce the incidence of postoperative lymphedema and accompanying symptoms, as well as to assess the comfort of using compression in women undergoing treatment for gynecological malignancies up to one year after surgery. The main objectives were to determine: Whether compression stockings applied immediately after radical surgery, in combination with physical activity, reduce the risk of developing lymphedema. Whether the use of compression stockings affects the quality of life. Whether compression stockings influence specific physical complaints related to the lower limbs. Patients were assessed preoperatively and at 3, 6, and 12 months postoperatively. Limb circumferences were measured at predefined anatomical points to calculate limb volume changes over time. Additionally, subjective symptoms, quality of life, and adherence to compression therapy were evaluated. Researchers compared a group using compression stockings with a control group without compression to analyze potential benefits and complications.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLymphedema
CountriesPoland
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedMar 13, 2025
Enrollment StartDec 1, 2016
Primary CompletionNov 29, 2020
Study CompletionDec 20, 2020
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 1.3 years ago

Interventions

compression productsother

Compression Group (CG): Participants received individually fitted, round-knit compression stockings with a pressure of 23-32 mmHg (Class 2, RAL-GZG standard). Compression garments were selected based on circumference measurements taken in the morning to ensure proper fit. Participants were instructed to wear the stockings for approximately 9 hours per day. The compression garments were provided by the same manufacturer (Medi GmbH \& Co., Bayreuth, Germany). Additionally, participants were advised to engage in daily physical activity (walking for at least 20 minutes per day) while wearing compression. Comprehensive education was provided on skin care, self-manual lymph drainage (simple lymph drainage, SLD), and lymphedema prevention.