CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,050 enrolled
Drug / intervention
Minimally invasive laparoscopic pull-through surgeryprocedure
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06874686
NCT06874686N/ACompleted

Minimally Invasive Laparoscopic Surgery for Hirschsprung's Disease: A Retrospective Study on Patient Safety Profiles, Effectiveness, and Short-term Functional Outcomes

National Children's Hospital, Vietnam·observational·Posted Mar 13, 2025·Updated Mar 17, 2025

In Brief

An observational study evaluating Minimally invasive laparoscopic pull-through surgery for Hirschsprung Disease. Completed, enrolled 1,050 participants across 1 site.

Detailed Summary

Hirschsprung's disease (HD) is a congenital disorder characterized by the absence of enteric ganglion cells in the distal bowel, leading to functional obstruction, delayed meconium passage in neonates, and chronic defecation difficulties. Surgical intervention is required to remove the aganglionic segment, with minimally invasive laparoscopic techniques increasingly preferred over open surgery due to reduced postoperative complications, shorter hospital stays, and faster recovery. Since 2012, the National Children's Hospital has pioneered the routine use of single-incision laparoscopic surgery (SILS) for HD in Vietnam. However, there is a lack of comprehensive analysis on the operative outcome in this large group of patients. This retrospective study aims to evaluate patient safety profiles, surgical effectiveness, and functional outcomes of minimally invasive laparoscopic procedures for HD performed at the National Children's Hospital between 2017 and 2023.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesVietnam
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedMar 13, 2025
Enrollment StartJan 1, 2017
Primary CompletionDec 1, 2023
Study CompletionFeb 1, 2025
TodayJul 2, 2026
Enrollment to primary: 6.9 yearsPosted 1.3 years ago

Interventions

Minimally invasive laparoscopic pull-through surgeryprocedure

Pediatric patients diagnosed with Hirschsprung's Disease from 2017-2023 at the National Children's Hospital underwent two minimally invasive procedures: conventional laparoscopic pull-through (CLP) and single-incision laparoscopic pull-through (SILPS). CLP involves three to five small incisions for trocars, allowing laparoscopic visualization and instrument access. Pneumoperitoneum is established, and the aganglionic colon segment is identified and mobilized using laparoscopic energy devices. The rectum is dissected circumferentially to preserve mesenteric blood supply, and a transanal approach is used to excise the diseased segment, followed by coloanal anastomosis with absorbable sutures. SILPS follows the same principles but is performed through a single umbilical incision using a multi-port device for all instruments. This technique offers benefits like reduced scarring and less postoperative pain but requires advanced laparoscopic skills due to instrument crowding.