At a glance
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Comparative Outcomes of Endoscopic and Open Carpal Tunnel Release with Neurotrophic Supplementation in Severe Carpal Tunnel Syndrome
In Brief
An observational study evaluating Endoscopic Carpal Tunnel Release, Open carpal tunnel release, and 1 other intervention for Carpal Tunnel Syndrome (CTS). Completed, enrolled 497 participants across 1 site.
Detailed Summary
This study addresses the pressing clinical question of optimizing surgical and pharmacological interventions for severe Carpal Tunnel Syndrome (CTS), a prevalent and debilitating condition caused by median nerve compression. Previous research has established the efficacy of Open Carpal Tunnel Release (OCTR) and Endoscopic Carpal Tunnel Release (ECTR); however, the role of neurotrophic supplementation in enhancing surgical outcomes has yet to be fully elucidated. Using a prospective clinical approach involving 497 patients, we evaluated the comparative outcomes of ECTR and OCTR with or without neurotrophic supplementation. Key findings demonstrate that ECTR, particularly when combined with neurotrophic agents, facilitates faster recovery and greater improvements in Sensory Nerve Conduction Velocity (VCS) and Visual Analog Scale (VAS) scores, with reduced complication rates compared to OCTR
Study Details
Timeline
Interventions
Release of carpal tunnel with endoscopic device
Release of carpal tunnel with open tecnique
Neurotrophic supplementation after surgery