CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 48 enrolled
Drug / intervention
Salivary and Serum TMAO Mesurement +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06906510
NCT06906510N/ACompleted
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Evaluation of Trimethylamine N-oxide (TMAO) Levels in Periodontal Disease

Ankara Medipol University·observational·Posted Apr 2, 2025·Updated Apr 2, 2025

In Brief

An observational study evaluating Salivary and Serum TMAO Mesurement and Salivary and Serum TNF-α Mesurement for Periodontitis and 3 related conditions. Completed, enrolled 48 participants across 1 site.

Detailed Summary

Salivary and serum levels of TMAO and TNF-α can distinguish between individuals with periodontitis and periodontally healthy individuals.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsPeriodontitis, Inflammation, Trimethylamine N-oxide (TMAO), TNF-alfa
CountriesTurkey (Türkiye)
CollaboratorsIstanbul Medipol University Hospital, Ankara University, Acibadem University, Lokman Hekim University

Timeline

N/ACompletedFinished
202420252026
First PostedApr 2, 2025
Enrollment StartJan 8, 2024
Primary CompletionAug 14, 2024
Study CompletionSep 23, 2024
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 1.3 years ago

Interventions

Salivary and Serum TMAO Mesurementother

Salivary and serum TMAO levels were measured by liquid chromatography-mass spectrometry (LC-MS/MS)

Salivary and Serum TNF-α Mesurementother

Salivary and serum TNF-α levels were measured by ELISA