CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 70 enrolled
Drug / intervention
Immediate access to customized version of GPT-4 +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06911645
NCT06911645N/ACompleted

Evaluating the Performance of LLMs and Clinicians in Complex Diagnostic Cases: A Randomized Controlled Trial

Stanford University·interventional·Posted Apr 4, 2025·Updated Apr 4, 2025

In Brief

A clinical study evaluating Immediate access to customized version of GPT-4 and Access to customized version of GPT-4 following use of conventional resources for Pathologic Processes and Disease. Completed, enrolled 70 participants across 1 site.

Detailed Summary

This study will assess the impact of immediate access to a customized version of GPT-4, a large language model, on performance in case-based diagnostic reasoning tasks. Specifically, it will compare this approach to a two-step process where participants first use traditional diagnostic decision support tools to support their diagnostic reasoning before gaining access to the customized GPT-4 model.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20252026
First PostedApr 4, 2025
Enrollment StartDec 16, 2024
Primary CompletionJan 24, 2025
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 1.2 years ago

Interventions

Immediate access to customized version of GPT-4other

Group is given immediate access to a customized version of GPT-4 to support their diagnostic reasoning for each case.

Access to customized version of GPT-4 following use of conventional resourcesother

Group is first encouraged to reason through diagnostic cases with the support of conventional resources. After they submit a case's answers they are then given access to a customized version of GPT-4 and have the opportunity to change their initial answers.