At a glance
ClinicalIndex Comparison RecordN/ACompleted· 233 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Utilizing CT Based Imaging Parameters of Body Composition to Understand Heterogeneity of Response to Biologic Therapies in Severe Asthma Cohorts
In Brief
An observational study for Asthma. Completed, enrolled 233 participants across 2 sites.
Detailed Summary
This study will utilize University of Michigan EMR data to form a retrospective cohort of severe asthma patients on biologic therapies for asthma with computed tomography (CT) imaging and known outcomes on therapy. These images will then be analyzed using morphomics, a combination of high-throughput image analysis and deep learning techniques, to derive imaging biomarkers that will be able to predict therapeutic response to biologics. These biomarkers will then be tested in a second cohort from the National Jewish Health to assess for validity.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
202120222023202420252026
Enrollment StartJan 2021
Primary CompletionJul 2024
First PostedApr 2025
TodayJul 2026
First PostedApr 10, 2025
Enrollment StartJan 15, 2021
Primary CompletionJul 31, 2024
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 1.2 years ago