CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Brief motivational interviewing with personalized feedback +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06924281
NCT06924281N/ACompleted

Team Science to Identify & Intervene on Metabolism- & Alcohol-Associated Liver Disease

Brown University·interventional·Posted Apr 11, 2025·Updated Feb 4, 2026

In Brief

A clinical study evaluating Brief motivational interviewing with personalized feedback and Brief motivational interviewing with standard health information for Steatotic Liver Disease of Mixed Origin (MetALD). Completed, enrolled 14 participants across 1 site.

Detailed Summary

Liver damage from alcohol intake and weight-related behaviors is preventable and treatable only through lifestyle changes. This mixed-methods randomized controlled trial compares standard and enhanced approaches to screening, brief intervention, and referral to treatment/prevention (SBIRT/P) to identify and intervene for metabolism- and alcohol-associated liver disease (MetALD). Our multidisciplinary team aims to show that integrating results of noninvasive liver screening with Fibroscan®, a painless ultrasound that measures stiffness and fat in the liver, can optimize our brief intervention. The study population is adults age 21+ who speak Spanish or English from underresourced communities with alcohol- and weight-related risks for MetALD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2026
First PostedApr 11, 2025
Enrollment StartApr 25, 2025
Primary CompletionAug 29, 2025
Study CompletionAug 31, 2025
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 1.2 years ago

Interventions

Brief motivational interviewing with personalized feedbackbehavioral

The manualized intervention is delivered individually in two phases by an interventionist trained in motivational interviewing. The intervention includes liver health information and explains connections with weight-related behaviors. The enhanced (experimental) group receives personalized feedback, i.e., a summary of self-reported drinking patterns and results of liver imaging with Fibroscan®, i.e., steatosis (liver fat) and fibrosis (liver scaring) scores. The feedback is used to develop discrepancies between a goal of halting or reversing health risks associated with consuming alcohol versus continuing to drink. The sessions are matched in duration and interventionist skill level with the standard (control) group.

Brief motivational interviewing with standard health informationbehavioral

The manualized intervention is delivered individually in two phases by an interventionist trained in motivational interviewing. The intervention includes liver health information and explains connections with weight-related behaviors. The standard (control) group does not receive personalized feedback. The sessions are matched in duration and interventionist skill level with the enhanced (experimental) group.