CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 92 enrolled / 92 target
Drug / intervention
Double Perclose Proglide +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06983938
NCT06983938N/ACompletedHigh Momentum (5.5/mo)Completion was 10mo ago

Randomized Trial Comparing Dual Perclose Vs Single Angioseal And Perclose in Patients Undergoing Transfemoral Transcatheter Aortic Valve Replacement

Baylor Research Institute·interventional·Posted May 21, 2025·Updated Jun 25, 2026

In Brief

A clinical study evaluating Double Perclose Proglide and Single Perclose Proglide plus Angioseal for Transcatheter Aortic Valve Replacement and Closure Technique. Completed, enrolled 92 participants across 1 site.

Signals

Enrolling ahead of pace

Detailed Summary

This prospective, randomized, parallel, single-center, open-label, non-inferiority study will evaluate the safety and potential complications of dual ProGlide vs single ProGlide and Angioseal for common femoral arteriotomy closure following Transcatheter Aortic Valve Replacement.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedMay 21, 2025
Enrollment StartFeb 12, 2025
Primary CompletionAug 13, 2025
Study CompletionOct 15, 2025
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 1.1 years ago

Arms & Interventions

Dual Perclose Proglideactive_comparator

Upon completion of valve replacement, this cohort will be closed using dual Perclose Proglide devices.

Device: Double Perclose Proglide
Single Perclose Proglide plus Angiosealactive_comparator

Upon completion of valve replacement, this cohort will be closed using a single Perclose Proglide device and single Angioseal device.

Device: Single Perclose Proglide plus Angioseal

Interventions

Double Perclose Proglidedevice

Upon completion of valve replacement, closure will proceed using two Perclose Proglide devices.

Single Perclose Proglide plus Angiosealdevice

Upon completion of valve replacement, closure will proceed using one Perclose Proglide device plus one Angioseal device.