CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 156 enrolled
Drug / intervention
Not applicable- observational studyother
Likely dose
Not stated in record
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Search/NCT07038291
NCT07038291N/ACompleted

Factors Associated With Extubation Failure in Kanigara ICU (Intensive Care Unit) RSUPN Dr. Cipto Mangunkusumo

Indonesia University·observational·Posted Jun 26, 2025·Updated Jun 26, 2025

In Brief

An observational study evaluating Not applicable- observational study for Extubation Failure and Ventilated Patients. Completed, enrolled 156 participants across 1 site.

Detailed Summary

Extubation is the final stage after patients undergo weaning procedure from mechanical ventilation in the ICU. Extubation failure followed by reintubation is associated with worse patient outcomes, including prolonged length of stay, increased risk of pulmonary infections, need for tracheostomy, higher healthcare costs, and increased mortality. Careful evaluation of various risk factors for extubation failure must be considered, therefore the extubation readiness guideline or checklist is essential before making the decision to extubate. This study aimed to identify factors associated with extubation failure in Kanigara ICU patients. This was a case-control study using secondary data from medical records of ICU patients who underwent extubation between January 2021 until August 2024. Variables analyzed included Glasgow Coma Scale (GCS) score, Arterial Blood Gas (ABG) results, hemodynamics, ventilator settings, airway protection ability, fluid balance, and airway-related problems. Bivariate and multivariate using logistic regression analyses were conducted to identify factors associated with extubation failure.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesIndonesia
Collaborators--

Timeline

N/ACompletedFinished
2026
First PostedJun 26, 2025
Enrollment StartMar 1, 2025
Primary CompletionMay 30, 2025
Study CompletionJun 5, 2025
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 1.0 years ago

Interventions

Not applicable- observational studyother

Observational study without intervention