CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 120 enrolled
Drug / intervention
High Purity Type-I Collagen-based Skin Substitute and SOC +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07046403
NCT07046403N/ACompleted

A Multicentric Randomized Controlled Clinical Trial Comparing the Use of High Purity Type-I Collagen-Based Skin Substitute vs. Dehydrated Human Amnion/Chorion Membrane in the Treatment of Diabetic Foot Ulcers

Adichunchanagiri Institute of Medical Sciences, B G Nagara·interventional·Posted Jul 1, 2025·Updated Nov 21, 2025

In Brief

A clinical study evaluating High Purity Type-I Collagen-based Skin Substitute and SOC and Dehydrated Human Amnion / Chorion Membrane and SOC for Diabetic Foot Ulcer (DFU). Completed, enrolled 120 participants across 4 sites.

Detailed Summary

This is a randomized controlled clinical investigation in patients suffering from diabetic foot ulcers at multiple centers. The study intends to compare patient outcome data using Standard of Care with Type-I Collagen-based Skin Substitute and Standard of Care with Dehydrated Human Amnion/Chorion Membrane.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndia

Timeline

N/ACompletedFinished
2026
First PostedJul 1, 2025
Enrollment StartJul 5, 2025
Primary CompletionSep 9, 2025
Study CompletionOct 3, 2025
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 1.0 years ago

Interventions

High Purity Type-I Collagen-based Skin Substitute and SOCdevice

The SOC in this study is wound care covering with High Purity Type-I Collagen-based Skin Substitute applied weekly or as needed followed by a padded 3-layer dressing comprised of first layer - non-adherent and porous paraffin gauze (Cuticel), second layer - absorbent 4x4 gauze pads \& third layer - soft roll and compressive wrap (Crepe Bandage)

Dehydrated Human Amnion / Chorion Membrane and SOCdevice

The SOC in this study is wound care covering with Dehydrated Human Amnion/Chorion Membrane followed by a padded 3-layer dressing comprised of first layer - non-adherent and porous paraffin gauze (Cuticel), second layer - absorbent 4x4 gauze pads \& third layer - soft roll and compressive wrap (Crepe Bandage)