CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
Pulmonary Rehabilitationother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07046442
NCT07046442N/ACompleted

Effect of Pulmonary Rehabilitation and Physical Activity on the Symptoms of Long COVID. A Pilot Study

University of Parma·observational·Posted Jul 1, 2025·Updated May 6, 2026

In Brief

An observational study evaluating Pulmonary Rehabilitation for COVID - 19. Completed, enrolled 40 participants across 1 site.

Detailed Summary

This single-center, observational, longitudinal, retrospective and prospective study investigates the impact of Active Cycle of Breathing Technique (ACBT) and moderate daily physical activity on symptoms associated with long COVID, such as cough, dyspnea, and fatigue. The study aims to assess whether these interventions can moderately alleviate or resolve these symptoms and evaluate their potential association with small airway dysfunction (SAD), as measured by Impulse Oscillometry (IOS). The investigators will recruit 40 adult patients with long COVID who meet specific inclusion criteria. Participants will perform ACBT twice daily and complete at least 6000 steps per day for six weeks. The investigators will track clinical and lung function parameters, including spirometry, IOS, and exercise capacity.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsCOVID - 19
CountriesItaly

Timeline

N/ACompletedFinished
2023202420252026
First PostedJul 1, 2025
Enrollment StartApr 5, 2022
Primary CompletionFeb 4, 2025
Study CompletionDec 30, 2025
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 1.0 years ago

Interventions

Pulmonary Rehabilitationother

The Active Cycle of Breathing Technique (ACBT), is a structured method aimed at restoring normal breathing patterns, improving respiratory muscle efficiency, and reducing airway irritation.