CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 102 enrolled / 102 target
Drug / intervention
CTI radiofrequency ablation.procedure
Likely dose
Not stated in record
Key inclusion· 2
  • Age 18 years or older
  • Undergoing CTI ablation
Key exclusion· 1
  • Prior right atrium ablation

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07078760
NCT07078760N/ACompletedOn Track (8.2/mo)Completion was 6mo ago

Lattice-tip Versus Irrigated-tip Catheter for Linear Ablation of the Cavotricuspid Isthmus. A Multicenter, Randomized Study. (The LINEAR Study)

Mitera Hospital·interventional·Posted Jul 22, 2025·Updated Jun 17, 2026

In Brief

A clinical study evaluating CTI radiofrequency ablation. for Catheter Ablation. Completed, enrolled 102 participants across 1 site.

Detailed Summary

The LINEAR study is designed to compare the procedural efficacy, efficiency and safety of linear radiofrequency ablation of the cavotricuspid istmus using either a standar irrigated-tip ablation catheter or lattice-tip ablation catheter .The primary focus of the acute procedural data analysis will be: Procedural efficacy: This will be evaluated based on the rate of bidirectional CTI block persistence after 60 min waiting period documented by high resolution activation mapping. Furthermore, provocative test with intravenous adenosine infusion will be conducted to exclude dormant CTI conduction. Procedural efficiency: This will be evaluated based on the number of RF lesions delivered, time to achieve bidirectional CTI block, and fluoroscopy exposure time. Procedural safety: The incidence of procedural complications will be recorded.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGreece
Collaborators--

Timeline

N/ACompletedFinished
2026
First PostedJul 22, 2025
Enrollment StartJun 16, 2025
Primary CompletionDec 11, 2025
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 11 months ago

Arms & Interventions

CTI radiofrequency ablation with lattice-tip catheteractive_comparator

Patients undergoing CTI catheter ablation using RF energy delivered by the lattice-tip, dual-energy catheter (Sphere-9, Medtronic).

Procedure: CTI radiofrequency ablation.
CTI radiofrequency ablation performed with irrigated-tip catheteractive_comparator

Patients undergoing CTI catheter ablation using RF energy delivered by the irrigated RF catheter (ThermoCool® SmartTouch™, Biosense Webster, USA).

Procedure: CTI radiofrequency ablation.

Interventions

CTI radiofrequency ablation.procedure

Cavotricuspid Isthmus ablation