At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Self-Sampling to Optimize Anal Lesion Outcomes (SOLO) Pilot
In Brief
A clinical study evaluating Inserting a swab 5 cm into the anus during self-sampling and Self-sampling with a swab by inserting the swab 3 cm into the anus. for Squamous Cell Carcinoma of the Anus. Completed, enrolled 50 participants across 1 site.
Detailed Summary
The investigators will test the cytological performance of a nylon-flocked swab at two insertion depths in the anus, 3 cm and 5 cm, to determine which insertion depth is better at collecting cells from the squamocolumnar junction (SCJ), an anatomic site that is particularly vulnerable to carcinogenic transformation. The investigators hypothesize that the 5 cm insertion will result in a higher quality specimen with cells from the SCJ. However, the deeper swab insertion may affect end user acceptability without increasing adequacy or quality.
Study Details
Timeline
Interventions
The swab will be inserted into the anus by the lay individual. The individual will insert the swab to a depth of 5 cm to collect anal exfoliated cells.
The swab will be inserted into the anus by the lay individual. The individual will insert the swab to a depth of 3 cm to collect anal exfoliated cells.