CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
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Search/NCT07105527
NCT07105527N/ACompleted

Dexmedetomidine During Carotid Endarterectomy: a Registry on Safety and Satisfaction of Patients and Operators (DexTEA)

Saint Camillus International University of Health Sciences·observational·Posted Aug 6, 2025·Updated Aug 12, 2025

In Brief

An observational study for Hypertension Arterial and 9 related conditions. Completed, enrolled 60 participants across 1 site.

Detailed Summary

From an anesthesiological perspective, carotid endarterectomy (CEA) is an operation that is increasingly being performed with locoregional techniques and sedation. The aim of this observational study was to compare dexmedetomidine with midazolam and fentanyl during CEA in terms of perioperative adverse events, patient, anesthetist, and surgeon satisfaction, as well as the possible reduction in clamping time and the number of times additional local anaesthesia is needed. Sixty patients listed for CEA were enrolled and two types of sedation were used, both protocols widely used in our hospital, resulting in the formation of two groups of patients. Both the intermediate and superficial cervical plexus blocks were administered, and the patients in Group 1 were sedated with midazolam and fentanyl, and Group 2 was sedated with dexmedetomidine. The investigators examined comorbidities, surgical time and clamping, and possible intraoperative use of local anaesthetics and intraprocedural complications, and follow-up at 180 days to observe any residual deficits. The data were analysed with Statistical Package for Social Science (SPSS) Statistics 25 (IBM).

Study Details

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedAug 6, 2025
Enrollment StartJan 8, 2021
Primary CompletionFeb 2, 2023
Study CompletionAug 2, 2023
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 11 months ago