CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled
Drug / intervention
Retention of the fissure sealants evaluatedother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07110701
NCT07110701N/ACompleted

A Comparative Clinical Evaluation of Two Resin-Based Fissure Sealants Applied With Different Isolation Techniques: An 18-Month Follow-Up Study

Izmir Katip Celebi University·interventional·Posted Aug 7, 2025·Updated Aug 7, 2025

In Brief

A clinical study evaluating Retention of the fissure sealants evaluated for Fissure Sealant and 2 related conditions. Completed, enrolled 100 participants across 1 site.

Detailed Summary

The aim of this clinical study was to evaluate the effects of different isolation methods and material filler ratios on the retention rates of two different fluoride-containing fissure sealants over an 18-month period. Methods: A total of 100 children (200 teeth) participated in this randomized, single-blind, split-mouth clinical trial. The mandibular permanent first molars of each participant were divided into two groups: one receiving a highly filled fluoride-releasing fissure sealant (Fissurit FX, Voco, Germany), and the other an unfilled fluoride-releasing sealant (Teethmate F-1, Kuraray, Germany). Each material group was also divided into two subgroups based on the isolation method used: rubber dam or cotton roll isolation. Sealant retention rates were evaluated at 6-, 12-, and 18-month follow-up visits. Data were statistically analyzed using a 0.05 significance level.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTurkey (Türkiye)
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedAug 7, 2025
Enrollment StartJun 15, 2023
Primary CompletionSep 15, 2023
Study CompletionMar 14, 2025
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 11 months ago

Interventions

Retention of the fissure sealants evaluatedother

Following classification system was employed for the retention evaluation of the sealants: 1 = complete retention; 2 = partial loss; or 3 = complete loss.