CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 46 enrolled
Drug / intervention
Ibuprofen 10 mg/kgdrug
Likely dose
Ibuprofen 10 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07114198
NCT07114198Early Ph 1Completed

Pain Management in Teeth With Reversible Pulpitis: A Randomised Controlled Trial

Inonu University·interventional·Posted Aug 11, 2025·Updated Sep 24, 2025

In Brief

A Early Phase 1 clinical trial evaluating Ibuprofen 10 mg/kg for Reversible Pulpitis and Ibuprofen. Completed, enrolled 46 participants across 1 site.

Detailed Summary

Effective intraoperative pain management is vital in paediatric dentistry, especially during vital pulp therapy (VPT) for reversible pulpitis. Although NSAIDs are widely used postoperatively, their role in controlling pain during treatment is less understood. To investigate the effect of preoperative ibuprofen on pain perception and physiological stress during VPT in children.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTurkey (Türkiye)
Collaborators--

Timeline

Early Ph 1CompletedFinished
2026
First PostedAug 11, 2025
Enrollment StartAug 2, 2025
Primary CompletionAug 11, 2025
Study CompletionAug 15, 2025
TodayJul 2, 2026
Enrollment to primary: 9 daysPosted 11 months ago

Interventions

Ibuprofen 10 mg/kgdrug

Ibuprofen was administered orally at a dose of 10 mg/kg body weight, 40 minutes before the start of the dental procedure. This intervention was designed to reduce intraoperative pain and pulse elevation associated with reversible pulpitis.