CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 90 enrolled
Drug / intervention
Lactobacillus casei Shirota +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07144475
NCT07144475Phase 4Completed

Comparison of Probiotic Effects of Lactobacillus Casei Shirota With Lactobacillus Acidophilus on the Outcomes of Patients After Colorectal Cancer Surgery: A Study of Gastrointestinal Function, Sepsis Incidence, C-Reactive Protein, Interleukin 6 and Length of Stay

Dharmais National Cancer Center Hospital·interventional·Posted Aug 27, 2025·Updated Aug 27, 2025

In Brief

A Phase 4 clinical trial evaluating Lactobacillus casei Shirota and Lactobacillus acidophilus for Colorectal Cancer. Completed, enrolled 90 participants across 1 site.

Detailed Summary

This clinical trial aims to compare the effects of administering Lactobacillus casei Shirota probiotics with Lactobacillus acidophilus on the outcomes of patients after colorectal cancer surgery. Researchers will compare probiotic to see if Lactobacillus casei Shirota improves gastrointestinal function, sepsis incidence, C-reactive protein (CRP), interleukin 6 (IL-6), and length of stay better than Lactobacillus acidophilus. Participants will take probiotics three times daily for three days before surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndonesia
Collaborators--

Timeline

Phase 4CompletedFinished
202420252026
First PostedAug 27, 2025
Enrollment StartJan 1, 2024
Primary CompletionNov 30, 2024
Study CompletionMar 4, 2025
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 10 months ago

Interventions

Lactobacillus casei Shirotabiological

Consumption of Lactobacillus casei Shirota three times daily for three days before surgery at 6 AM, 2 PM and 10 PM.

Lactobacillus acidophilusbiological

Consumption of Lactobacillus acidophilus three times daily for three days before surgery at 6 AM, 2 PM and 10 PM.