CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 72 enrolled
Drug / intervention
Aion Tempshield Devicedevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07145541
NCT07145541N/ACompleted

A Prospective, Interventional Study Assessing the Effectiveness of the AION BIOSYSTEMS, INC. TempShield ("Shield") for Continuous Temperature Monitoring Device in the Pediatric Emergency Depart

AION Biosystems·interventional·Posted Aug 28, 2025·Updated Nov 19, 2025

In Brief

A clinical study evaluating Aion Tempshield Device for Fever and Sepsis. Completed, enrolled 72 participants across 1 site.

Detailed Summary

The purpose of this research study is to evaluate the effectiveness of the AION BIOSYTEMS, INC. tempshield ("Shield") temperature monitoring device and platform in detecting body temperature for children 2-4 years old. The ED Research team will be deploying this device on all qualified patients who are awaiting inpatient admission from the emergency department and who have consented to participating in the study. Patients will be asked to keep the device on for a maximum of 7 hours during their stay in the emergency department. There is a potential clinical benefit that fevers will be detected earlier in subjects wearing the AION BIOSTYEMS, INC. tempshield. It is hoped that information gained from the study will help assist clinical care workflow and the treatment of future patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFever, Sepsis
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedAug 28, 2025
Enrollment StartJan 31, 2024
Primary CompletionOct 10, 2024
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 10 months ago

Interventions

Aion Tempshield Devicedevice

The AION BIOSYSTEMS, INC. tempshield is a skin-applied, continuous temperature monitor. It is battery powered, communicates using Bluetooth LE to a smartphone, then to a clinician dashboard, and is designed to be worn continuously for up to 60 days. Its primary use is for patient monitoring in hospital or post-discharge from a healthcare facility. Through the tempshield system, clinicians can be notified if a patient's temperature exceeds a given threshold. The tempshield system is centered around a non-invasive temperature sensor placed against the patient's skin, in the pectoral region just below the collar bone. The temperature sensor is held in place with a silicone adhesive tape similar to a custom shaped piece of medical tape. The silicone adhesive tape is hypoallergenic.